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RB1 dual role in proliferation and apoptosis: Cell fate control and implications for cancer therapy

Inactivation of the retinoblastoma (RB1) tumor suppressor is one of the most frequent and early recognized molecular hallmarks of cancer. RB1, although mainly studied for its role in the regulation of cell cycle, emerged as a key regulator of many biological processes. Among these, RB1 has been impl...

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Detalles Bibliográficos
Autores principales: Indovina, Paola, Pentimalli, Francesca, Casini, Nadia, Vocca, Immacolata, Giordano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627222/
https://www.ncbi.nlm.nih.gov/pubmed/26160835