A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas

Meningiomas are the most common primary intracranial adult tumor. All Neurofibromatosis 2 (NF2)-associated meningiomas and ~60% of sporadic meningiomas show loss of NF2 tumor suppressor protein. There are no effective medical therapies for progressive and recurrent meningiomas. Our previous work dem...

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Detalles Bibliográficos
Autores principales: Beauchamp, Roberta L., James, Marianne F., DeSouza, Patrick A., Wagh, Vilas, Zhao, Wen-Ning, Jordan, Justin T., Stemmer-Rachamimov, Anat, Plotkin, Scott R., Gusella, James F., Haggarty, Stephen J., Ramesh, Vijaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627286/
https://www.ncbi.nlm.nih.gov/pubmed/26219339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627286/
https://www.ncbi.nlm.nih.gov/pubmed/26219339

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