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MicroRNA-125a influences breast cancer stem cells by targeting leukemia inhibitory factor receptor which regulates the hippo signaling pathway

Cancer stem cells (CSC) are the main driving force behind cancer initiation and progression. The molecular mechanisms that regulate CSC properties are poorly understood. MicroRNAs (miRNAs) play a significant role in normal and cancer tissues. Here, we show that miRNA-125a indirectly regulates TAZ, a...

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Detalles Bibliográficos
Autores principales: Nandy, Sushmita Bose, Arumugam, Arunkumar, Subramani, Ramadevi, Pedroza, Diego, Hernandez, Keziah, Saltzstein, Edward, Lakshmanaswamy, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627314/
https://www.ncbi.nlm.nih.gov/pubmed/25962054