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Novel roles of TMEM100: inhibition metastasis and proliferation of hepatocellular carcinoma

Transmembrane protein 100 (TMEM100) was activated by ALK1/TGF-β signaling. We found that TMEM100 was decreased in hepatocellular carcinoma (HCC) tissues and in highly metastatic cell lines. Overexpressed of TMEM100 inhibited invasion, migration and proliferation. Low levels of TMEM100 were associate...

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Detalles Bibliográficos
Autores principales: Ou, Dipeng, Yang, Hao, Hua, Dong, Xiao, Shuai, Yang, Lianyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627315/
https://www.ncbi.nlm.nih.gov/pubmed/25978032