EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy

The combination of time and order-dependent chemotherapeutic strategies has demonstrated enhanced efficacy in killing cancer cells while minimizing adverse effects. However, the precise mechanism remains elusive. Our results showed that pre-treatment of MCF-7 and MDA-MB-468 cells with epidermal grow...

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Detalles Bibliográficos
Autores principales: Li, Yun-Tian, Qian, Xiao-Jun, Yu, Yan, Li, Zhen-Hua, Wu, Rui-Yan, Ji, Jiao, Jiao, Lin, Li, Xuan, Kong, Peng-Fei, Chen, Wen-Dan, Feng, Gong-Kan, Deng, Rong, Zhu, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627323/
https://www.ncbi.nlm.nih.gov/pubmed/26036637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627323/
https://www.ncbi.nlm.nih.gov/pubmed/26036637

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