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Buprenorphine-elicited alteration of adenylate cyclase activity in human embryonic kidney 293 cells coexpressing κ-, μ-opioid and nociceptin receptors

Buprenorphine, a maintenance drug for heroin addicts, exerts its pharmacological function via κ- (KOP), μ-opioid (MOP) and nociceptin/opioid receptor-like 1 (NOP) receptors. Previously, we investigated its effects in an in vitro model expressing human MOP and NOP receptors individually or simultaneo...

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Detalles Bibliográficos
Autores principales: Wang, Pei-Chen, Ho, Ing-Kang, Lee, Cynthia Wei-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627564/
https://www.ncbi.nlm.nih.gov/pubmed/26153065
http://dx.doi.org/10.1111/jcmm.12644