Doxycycline reduces the migration of tuberous sclerosis complex-2 null cells - effects on RhoA-GTPase and focal adhesion kinase

Lymphangioleiomyomatosis (LAM) is associated with dysfunction of the tuberous sclerosis complex (TSC) leading to enhanced cell proliferation and migration. This study aims to examine whether doxycycline, a tetracycline antibiotic, can inhibit the enhanced migration of TSC2-deficient cells, identify...

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Detalles Bibliográficos
Autores principales: Ng, Ho Yin, Oliver, Brian Gregory George, Burgess, Janette Kay, Krymskaya, Vera P, Black, Judith Lee, Moir, Lyn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627568/
https://www.ncbi.nlm.nih.gov/pubmed/26282580
http://dx.doi.org/10.1111/jcmm.12593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627568/
https://www.ncbi.nlm.nih.gov/pubmed/26282580
http://dx.doi.org/10.1111/jcmm.12593

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