Characterizing noise structure in single-cell RNA-seq distinguishes genuine from technical stochastic allelic expression

Single-cell RNA-sequencing (scRNA-seq) facilitates identification of new cell types and gene regulatory networks as well as dissection of the kinetics of gene expression and patterns of allele-specific expression. However, to facilitate such analyses, separating biological variability from the high...

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Detalles Bibliográficos
Autores principales: Kim, Jong Kyoung, Kolodziejczyk, Aleksandra A., Illicic, Tomislav, Teichmann, Sarah A., Marioni, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627577/
https://www.ncbi.nlm.nih.gov/pubmed/26489834
http://dx.doi.org/10.1038/ncomms9687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627577/
https://www.ncbi.nlm.nih.gov/pubmed/26489834
http://dx.doi.org/10.1038/ncomms9687

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