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Downregulation of toll-like receptor 4 induces suppressive effects on hepatitis B virus-related hepatocellular carcinoma via ERK1/2 signaling

BACKGROUND: Hepatitis B virus (HBV) infection is a major risk factor which can lead to development of hepatocellular carcinoma (HCC). In this study, we aimed to explore the effects of toll-like receptor 4 (TLR4) downregulation on the growth and survival of HBV-related HCC cells and to examine the mo...

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Detalles Bibliográficos
Autores principales: Wang, Yiting, Cai, Jing, Zeng, Xiaoli, Chen, Yajie, Yan, Wei, Ouyang, Yuming, Xiao, Dan, Zeng, Zhiming, Huang, Long, Liu, Anwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627624/
https://www.ncbi.nlm.nih.gov/pubmed/26514586
http://dx.doi.org/10.1186/s12885-015-1866-9