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Composition of Overlapping Protein-Protein and Protein-Ligand Interfaces
Protein-protein interactions (PPIs) play a major role in many biological processes and they represent an important class of targets for therapeutic intervention. However, targeting PPIs is challenging because often no convenient natural substrates are available as starting point for small-molecule d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627654/ https://www.ncbi.nlm.nih.gov/pubmed/26517868 http://dx.doi.org/10.1371/journal.pone.0140965 |