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Composition of Overlapping Protein-Protein and Protein-Ligand Interfaces

Protein-protein interactions (PPIs) play a major role in many biological processes and they represent an important class of targets for therapeutic intervention. However, targeting PPIs is challenging because often no convenient natural substrates are available as starting point for small-molecule d...

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Detalles Bibliográficos
Autores principales: Mohamed, Ruzianisra, Degac, Jennifer, Helms, Volkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627654/
https://www.ncbi.nlm.nih.gov/pubmed/26517868
http://dx.doi.org/10.1371/journal.pone.0140965