Computational Design of Hypothetical New Peptides Based on a Cyclotide Scaffold as HIV gp120 Inhibitor

Cyclotides are a family of triple disulfide cyclic peptides with exceptional resistance to thermal/chemical denaturation and enzymatic degradation. Several cyclotides have been shown to possess anti-HIV activity, including kalata B1 (KB1). However, the use of cyclotides as anti-HIV therapies remains...

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Detalles Bibliográficos
Autores principales: Sangphukieo, Apiwat, Nawae, Wanapinun, Laomettachit, Teeraphan, Supasitthimethee, Umaporn, Ruengjitchatchawalya, Marasri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627658/
https://www.ncbi.nlm.nih.gov/pubmed/26517259
http://dx.doi.org/10.1371/journal.pone.0139562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627658/
https://www.ncbi.nlm.nih.gov/pubmed/26517259
http://dx.doi.org/10.1371/journal.pone.0139562

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