A Computational Study of the Effects of Syk Activity on B Cell Receptor Signaling Dynamics

The kinase Syk is intricately involved in early signaling events in B cells and is required for proper response when antigens bind to B cell receptors (BCRs). Experiments using an analog-sensitive version of Syk (Syk-AQL) have better elucidated its role, but have not completely characterized its beh...

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Detalles Bibliográficos
Autores principales: McGee, Reginald L., Krisenko, Mariya O., Geahlen, Robert L., Rundell, Ann E., Buzzard, Gregery T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627698/
https://www.ncbi.nlm.nih.gov/pubmed/26525178
http://dx.doi.org/10.3390/pr3010075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627698/
https://www.ncbi.nlm.nih.gov/pubmed/26525178
http://dx.doi.org/10.3390/pr3010075

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