Cargando…
A Computational Study of the Effects of Syk Activity on B Cell Receptor Signaling Dynamics
The kinase Syk is intricately involved in early signaling events in B cells and is required for proper response when antigens bind to B cell receptors (BCRs). Experiments using an analog-sensitive version of Syk (Syk-AQL) have better elucidated its role, but have not completely characterized its beh...
Autores principales: | McGee, Reginald L., Krisenko, Mariya O., Geahlen, Robert L., Rundell, Ann E., Buzzard, Gregery T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627698/ https://www.ncbi.nlm.nih.gov/pubmed/26525178 http://dx.doi.org/10.3390/pr3010075 |
Ejemplares similares
-
Nanomechanical Property Maps of Breast Cancer Cells
As Determined by Multiharmonic Atomic Force Microscopy Reveal Syk-Dependent
Changes in Microtubule
Stability Mediated by MAP1B
por: Krisenko, Mariya O., et al.
Publicado: (2014) -
Efficient Optimization of Stimuli for Model-Based Design of Experiments to Resolve Dynamical Uncertainty
por: Mdluli, Thembi, et al.
Publicado: (2015) -
Modeling Mitochondrial Bioenergetics with Integrated Volume Dynamics
por: Bazil, Jason N., et al.
Publicado: (2010) -
Multiple Model-Informed Open-Loop Control of Uncertain Intracellular Signaling Dynamics
por: Perley, Jeffrey P., et al.
Publicado: (2014) -
Modulation of BCR Signaling by the Induced Dimerization of Receptor-Associated SYK
por: Westbroek, Mark L., et al.
Publicado: (2017)