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Targeted Therapy for MAPK Alterations in Pediatric Gliomas

Although the mitogen-activated protein kinase (MAPK) pathway helps promote normal cell development, the pathway is known to contribute to the initiation and growth of many types of cancers. Tumorigenesis can result from mutations in a number of the pathway’s key proteins, including but not limited t...

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Detalles Bibliográficos
Autores principales: Truong, AY, Nicolaides, TP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627711/
https://www.ncbi.nlm.nih.gov/pubmed/26525348
http://dx.doi.org/10.4172/2168-975X.S2-005