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Targeted Therapy for MAPK Alterations in Pediatric Gliomas
Although the mitogen-activated protein kinase (MAPK) pathway helps promote normal cell development, the pathway is known to contribute to the initiation and growth of many types of cancers. Tumorigenesis can result from mutations in a number of the pathway’s key proteins, including but not limited t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627711/ https://www.ncbi.nlm.nih.gov/pubmed/26525348 http://dx.doi.org/10.4172/2168-975X.S2-005 |