Curcumin Mitigates the Intracellular Lipid Deposit Induced by Antipsychotics In Vitro

SCOPE: First- and second-generation antipsychotics (FGAs and SGAs, respectively), both inhibit cholesterol biosynthesis and impair the intracellular cholesterol trafficking, leading to lipid accumulation in the late endosome/lysosome compartment. In this study we examined if curcumin, a plant polyph...

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Detalles Bibliográficos
Autores principales: Canfrán-Duque, Alberto, Pastor, Oscar, Reina, Manuel, Lerma, Milagros, Cruz-Jentoft, Alfonso J., Lasunción, Miguel A., Busto, Rebeca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627744/
https://www.ncbi.nlm.nih.gov/pubmed/26517556
http://dx.doi.org/10.1371/journal.pone.0141829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627744/
https://www.ncbi.nlm.nih.gov/pubmed/26517556
http://dx.doi.org/10.1371/journal.pone.0141829

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