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Curcumin Mitigates the Intracellular Lipid Deposit Induced by Antipsychotics In Vitro

SCOPE: First- and second-generation antipsychotics (FGAs and SGAs, respectively), both inhibit cholesterol biosynthesis and impair the intracellular cholesterol trafficking, leading to lipid accumulation in the late endosome/lysosome compartment. In this study we examined if curcumin, a plant polyph...

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Detalles Bibliográficos
Autores principales:	Canfrán-Duque, Alberto, Pastor, Oscar, Reina, Manuel, Lerma, Milagros, Cruz-Jentoft, Alfonso J., Lasunción, Miguel A., Busto, Rebeca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627744/ https://www.ncbi.nlm.nih.gov/pubmed/26517556 http://dx.doi.org/10.1371/journal.pone.0141829

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