Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration

BACKGROUND: The human retinal pigment epithelium (RPE) plays an important role in the pathogenesis of age related macular degeneration (AMD). AMD is the leading cause of blindness worldwide. There is currently no effective treatment available. Preclinical studies in AMD mouse models are essential to...

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Detalles Bibliográficos
Autores principales: Bennis, Anna, Gorgels, Theo G. M. F., ten Brink, Jacoline B., van der Spek, Peter J., Bossers, Koen, Heine, Vivi M., Bergen, Arthur A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627757/
https://www.ncbi.nlm.nih.gov/pubmed/26517551
http://dx.doi.org/10.1371/journal.pone.0141597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627757/
https://www.ncbi.nlm.nih.gov/pubmed/26517551
http://dx.doi.org/10.1371/journal.pone.0141597

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