Cargando…

Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration

BACKGROUND: The human retinal pigment epithelium (RPE) plays an important role in the pathogenesis of age related macular degeneration (AMD). AMD is the leading cause of blindness worldwide. There is currently no effective treatment available. Preclinical studies in AMD mouse models are essential to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bennis, Anna, Gorgels, Theo G. M. F., ten Brink, Jacoline B., van der Spek, Peter J., Bossers, Koen, Heine, Vivi M., Bergen, Arthur A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627757/ https://www.ncbi.nlm.nih.gov/pubmed/26517551 http://dx.doi.org/10.1371/journal.pone.0141597

Ejemplares similares

Comparative gene expression study and pathway analysis of the human iris- and the retinal pigment epithelium
por: Bennis, Anna, et al.
Publicado: (2017)

Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium.
por: Bennis, A., et al.
Publicado: (2017)

Functional annotation of the human retinal pigment epithelium transcriptome
por: Booij, Judith C, et al.
Publicado: (2009)

Gene expression and functional annotation of human choroid plexus epithelium failure in Alzheimer’s disease
por: Bergen, Arthur A., et al.
Publicado: (2015)

Gene Expression and Functional Annotation of the Human and Mouse Choroid Plexus Epithelium
por: Janssen, Sarah F., et al.
Publicado: (2013)

Gene Expression and Functional Annotation of the Human Ciliary Body Epithelia
por: Janssen, Sarah F., et al.
Publicado: (2012)

Gene expression-based comparison of the human secretory neuroepithelia of the brain choroid plexus and the ocular ciliary body: potential implications for glaucoma
por: Janssen, Sarah F, et al.
Publicado: (2014)

Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration
por: Lenis, Tamara L., et al.
Publicado: (2018)

Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration
por: Senabouth, Anne, et al.
Publicado: (2022)

NLRP3 Upregulation in Retinal Pigment Epithelium in Age-Related Macular Degeneration
por: Wang, Yujuan, et al.
Publicado: (2016)

Molecular Mechanisms of Retinal Pigment Epithelium Dysfunction in Age-Related Macular Degeneration
por: Kim, Jongmin, et al.
Publicado: (2021)

Dissecting Regulators of Aging and Age-Related Macular Degeneration in the Retinal Pigment Epithelium
por: Karunadharma, Pabalu P., et al.
Publicado: (2022)

The ERCC6 Gene and Age-Related Macular Degeneration
por: Baas, Dominique C., et al.
Publicado: (2010)

Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration
por: Voigt, Andrew P., et al.
Publicado: (2019)

Evaluation of retinal pigment epithelium changes in serous pigment epithelial detachment in age-related macular degeneration
por: Miura, Masahiro, et al.
Publicado: (2021)

The Aged Retinal Pigment Epithelium/Choroid: A Potential Substratum for the Pathogenesis of Age-Related Macular Degeneration
por: Chen, Huiyi, et al.
Publicado: (2008)

Concise Review: Update on Retinal Pigment Epithelium Transplantation for Age‐Related Macular Degeneration
por: Zarbin, Marco, et al.
Publicado: (2019)

The Cytoskeleton of the Retinal Pigment Epithelium: from Normal Aging to Age-Related Macular Degeneration
por: Tarau, Ioana-Sandra, et al.
Publicado: (2019)

Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration
por: Kaarniranta, Kai, et al.
Publicado: (2016)

Sub-retinal pigment epithelium tubules in non-neovascular age-related macular degeneration
por: Fragiotta, Serena, et al.
Publicado: (2022)

Sodium-Iodate Injection Can Replicate Retinal Degenerative Disease Stages in Pigmented Mice and Rats: Non-Invasive Follow-Up Using OCT and ERG
por: Koster, Céline, et al.
Publicado: (2022)

Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration
por: Wang, Ai Ling, et al.
Publicado: (2009)

Slow progression of exudative age related macular degeneration associated with hypertrophy of the retinal pigment epithelium
por: Stern, Jeffrey, et al.
Publicado: (2014)

Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration
por: Gambril, J. Alan, et al.
Publicado: (2019)

Retinal pigment epithelium and age‐related macular degeneration: A review of major disease mechanisms
por: Somasundaran, Shreya, et al.
Publicado: (2020)

Automated evaluation of retinal pigment epithelium disease area in eyes with age-related macular degeneration
por: Motozawa, Naohiro, et al.
Publicado: (2022)

Inflammasome Activation in Retinal Pigment Epithelium from Human Donors with Age-Related Macular Degeneration
por: Ebeling, Mara C., et al.
Publicado: (2022)

Prolonged Lifetimes of Histologic Autofluorescence in Ectopic Retinal Pigment Epithelium in Age-Related Macular Degeneration
por: Simon, Rowena, et al.
Publicado: (2022)

Membrane Attack Complex Mediates Retinal Pigment Epithelium Cell Death in Stargardt Macular Degeneration
por: Ng, Eunice Sze Yin, et al.
Publicado: (2022)

Clinical Characteristics of Eyes with Neovascular Age-Related Macular Degeneration and Retinal Pigment Epithelium Tears
por: Nagata, Junya, et al.
Publicado: (2023)

Directional protein secretion by the retinal pigment epithelium: roles in retinal health and the development of age-related macular degeneration
por: Kay, Paul, et al.
Publicado: (2013)

Rev-Erbα and Photoreceptor Outer Segments modulate the Circadian Clock in Retinal Pigment Epithelial Cells
por: Milićević, Nemanja, et al.
Publicado: (2019)

Involvement of the Retinal Pigment Epithelium in the Development of Retinal Lattice Degeneration
por: Mizuno, Hiroshi, et al.
Publicado: (2020)

Oxidative stress in retinal pigment epithelium degeneration: from pathogenesis to therapeutic targets in dry age-related macular degeneration
por: Maurya, Meenakshi, et al.
Publicado: (2023)

A Systematic Review on Transplantation Studies of the Retinal Pigment Epithelium in Animal Models
por: Koster, Céline, et al.
Publicado: (2020)

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration
por: Kaarniranta, Kai, et al.
Publicado: (2013)

Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular Degeneration
por: Curcio, Christine A., et al.
Publicado: (2017)

Integrated Microarray and RNAseq Transcriptomic Analysis of Retinal Pigment Epithelium/Choroid in Age-Related Macular Degeneration
por: Dhirachaikulpanich, Dhanach, et al.
Publicado: (2020)

D609 protects retinal pigmented epithelium as a potential therapy for age-related macular degeneration
por: Wang, Bowen, et al.
Publicado: (2020)

Progressive Dysmorphia of Retinal Pigment Epithelium in Age-Related Macular Degeneration Investigated by Fluorescence Lifetime Imaging
por: Hammer, Martin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fh9ob2i5nqffe4o90lftbjddtm