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Orally-Induced Intestinal CD4(+) CD25(+) FoxP3(+) Treg Controlled Undesired Responses towards Oral Antigens and Effectively Dampened Food Allergic Reactions

The induction of peripheral tolerance may constitute a disease-modifying treatment for allergic patients. We studied how oral immunotherapy (OIT) with milk proteins controlled allergy in sensitized mice (cholera toxin plus milk proteins) upon exposure to the allergen. Symptoms were alleviated, skin...

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Detalles Bibliográficos
Autores principales: Smaldini, Paola Lorena, Orsini Delgado, María Lucía, Fossati, Carlos Alberto, Docena, Guillermo Horacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627767/
https://www.ncbi.nlm.nih.gov/pubmed/26517875
http://dx.doi.org/10.1371/journal.pone.0141116