Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity

Functional selectivity (or biased agonism) is a property exhibited by some G protein-coupled receptor (GPCR) ligands, which results in the modulation of a subset of a receptor’s signaling capabilities and more precise control over complex biological processes. The dopamine D2 receptor (D(2)R) exhibi...

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Detalles Bibliográficos
Autores principales: Peterson, Sean M., Pack, Thomas F., Caron, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627803/
https://www.ncbi.nlm.nih.gov/pubmed/26516769
http://dx.doi.org/10.1371/journal.pone.0141637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627803/
https://www.ncbi.nlm.nih.gov/pubmed/26516769
http://dx.doi.org/10.1371/journal.pone.0141637

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