NSAIDs Alter Phosphorylated Forms of AQP2 in the Inner Medullary Tip

Vasopressin increases urine concentration through activation of aquaporin-2 (AQP2) in the collecting duct. Nonsteroidal anti-inflammatory drugs (NSAIDs) block prostaglandin E2 synthesis, and may suppress AQP2 producing a urine concentrating defect. There are four serines in AQP2 that are phosphoryla...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Huiwen, Yang, Baoxue, Molina, Patrick A., Sands, Jeff M., Klein, Janet D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627840/
https://www.ncbi.nlm.nih.gov/pubmed/26517129
http://dx.doi.org/10.1371/journal.pone.0141714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627840/
https://www.ncbi.nlm.nih.gov/pubmed/26517129
http://dx.doi.org/10.1371/journal.pone.0141714

Ejemplares similares