Promoter methylation of TRIM9 as a marker for detection of circulating tumor DNA in breast cancer patients

The aim of the present study was to investigate the promoter methylation status of TRIM9 in breast cancer and to determine the presence of TRIM9-methylated circulating tumor DNA (ctDNA) in plasma. Bisulfite sequencing with a next generation sequencer showed TRIM9 promoter methylation in 92 % (11/12)...

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Detalles Bibliográficos
Autores principales: Mishima, Chieko, Kagara, Naofumi, Matsui, Saki, Tanei, Tomonori, Naoi, Yasuto, Shimoda, Masafumi, Shimomura, Atsushi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627990/
https://www.ncbi.nlm.nih.gov/pubmed/26543769
http://dx.doi.org/10.1186/s40064-015-1423-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627990/
https://www.ncbi.nlm.nih.gov/pubmed/26543769
http://dx.doi.org/10.1186/s40064-015-1423-7

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