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Promoter methylation of TRIM9 as a marker for detection of circulating tumor DNA in breast cancer patients
The aim of the present study was to investigate the promoter methylation status of TRIM9 in breast cancer and to determine the presence of TRIM9-methylated circulating tumor DNA (ctDNA) in plasma. Bisulfite sequencing with a next generation sequencer showed TRIM9 promoter methylation in 92 % (11/12)...
Autores principales: | Mishima, Chieko, Kagara, Naofumi, Matsui, Saki, Tanei, Tomonori, Naoi, Yasuto, Shimoda, Masafumi, Shimomura, Atsushi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627990/ https://www.ncbi.nlm.nih.gov/pubmed/26543769 http://dx.doi.org/10.1186/s40064-015-1423-7 |
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