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Erlotinib augmentation with dapsone for rash mitigation and increased anti-cancer effectiveness

BACKGROUND: The epidermal growth factor receptor tyrosine kinase inhibitor erlotinib has failed in many ways to be as potent in the anti-cancer role as pre-clinical studies would have suggested. This paper traces some aspects of this failure to a compensatory erlotinib-mediated increase in interleuk...

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Detalles Bibliográficos
Autor principal: Kast, R. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628020/
https://www.ncbi.nlm.nih.gov/pubmed/26543772
http://dx.doi.org/10.1186/s40064-015-1441-5