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A cell-free enzymatic activity assay for the evaluation of HIV-1 drug resistance to protease inhibitors
Due to their high frequency of genomic mutations, human retroviruses often develop resistance to antiretroviral drugs. The emergence of drug-resistant human immunodeficiency virus type 1 (HIV-1) is a significant obstacle to the effective long-term treatment of HIV infection. The development of a rap...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628118/ https://www.ncbi.nlm.nih.gov/pubmed/26583013 http://dx.doi.org/10.3389/fmicb.2015.01220 |