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HMMvar-func: a new method for predicting the functional outcome of genetic variants
BACKGROUND: Numerous tools have been developed to predict the fitness effects (i.e., neutral, deleterious, or beneficial) of genetic variants on corresponding proteins. However, prediction in terms of whether a variant causes the variant bearing protein to lose the original function or gain new func...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628267/ https://www.ncbi.nlm.nih.gov/pubmed/26518340 http://dx.doi.org/10.1186/s12859-015-0781-z |