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Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy

BACKGROUND: Malaria remains a challenging and fatal infectious disease in developing nations and the urgency for the development of new drugs is even greater due to the rapid spread of anti-malarial drug resistance. While numerous parasite genetic, protein and metabolite biomarkers have been propose...

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Detalles Bibliográficos
Autores principales: Deng, Xiaoyan, Duffy, Simon P., Myrand-Lapierre, Marie-Eve, Matthews, Kerryn, Santoso, Aline Teresa, Du, Yi-Ling, Ryan, Katherine S., Ma, Hongshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628286/
https://www.ncbi.nlm.nih.gov/pubmed/26520795
http://dx.doi.org/10.1186/s12936-015-0957-z