Evaluation of the pathogenicity of West Nile virus (WNV) lineage 2 strains in a SPF chicken model of infection: NS3-249Pro mutation is neither sufficient nor necessary for conferring virulence

Lineage 2 West Nile virus (WNV) strains were reported for the first time in Europe in 2004. Despite an almost silent circulation around their entry point in Hungary, an upsurge of pathogenicity occurred in 2010 as 262 people suffered from neuroinvasive disease in Greece. This increase in virulence w...

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Detalles Bibliográficos
Autores principales: Dridi, Maha, Van Den Berg, Thierry, Lecollinet, Sylvie, Lambrecht, Benedicte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628354/
https://www.ncbi.nlm.nih.gov/pubmed/26518144
http://dx.doi.org/10.1186/s13567-015-0257-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628354/
https://www.ncbi.nlm.nih.gov/pubmed/26518144
http://dx.doi.org/10.1186/s13567-015-0257-1

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