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Necrotizing Enterocolitis in a mouse model leads to widespread renal inflammation, acute kidney injury and disruption of renal tight junction proteins

BACKGROUND: Necrotizing enterocolitis (NEC) is a devastating condition affecting premature infants and leads to high mortality and chronic morbidity. Severe form of NEC is associated with acute renal failure, fluid imbalance, hyponatremia and acidosis. We investigated the effect of NEC on tight junc...

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Detalles Bibliográficos
Autores principales: Garg, Parvesh M, Tatum, Rodney, Ravisankar, Srikanth, Shekhawat, Prem S, Chen, Yan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628581/
https://www.ncbi.nlm.nih.gov/pubmed/26270572
http://dx.doi.org/10.1038/pr.2015.146