Heterochromatic breaks move to the nuclear periphery to continue recombinational repair

Heterochromatin mostly comprises repeated sequences prone to harmful ectopic recombination during double-strand break (DSB) repair. In Drosophila cells, ‘safe’ homologous recombination (HR) repair of heterochromatic breaks relies on a specialized pathway that relocalizes damaged sequences away from...

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Detalles Bibliográficos
Autores principales: Ryu, Taehyun, Spatola, Brett, Delabaere, Laetitia, Bowlin, Katherine, Hopp, Hannah, Kunitake, Ryan, Karpen, Gary H., Chiolo, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628585/
https://www.ncbi.nlm.nih.gov/pubmed/26502056
http://dx.doi.org/10.1038/ncb3258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628585/
https://www.ncbi.nlm.nih.gov/pubmed/26502056
http://dx.doi.org/10.1038/ncb3258

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