Mitochondrial DNA mutations distinguish bilateral multifocal renal oncocytomas from familial Birt-Hogg-Dubé tumors

Oncocytomas are mostly benign tumors characterized by accumulation of defective mitochondria, and in sporadic cases, are associated with disruptive mitochondrial DNA (mtDNA) mutations. However, the role mtDNA mutations play in renal tumors of Birt-Hogg-Dubé (BHD) patients and other renal oncocytomas...

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Detalles Bibliográficos
Autores principales: Lang, Martin, Vocke, Cathy D., Merino, Maria J., Schmidt, Laura S., Linehan, W. Marston
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628590/
https://www.ncbi.nlm.nih.gov/pubmed/26428318
http://dx.doi.org/10.1038/modpathol.2015.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628590/
https://www.ncbi.nlm.nih.gov/pubmed/26428318
http://dx.doi.org/10.1038/modpathol.2015.101

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