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Respiratory Syncytial Virus Nonstructural Proteins Upregulate SOCS1 and SOCS3 in the Different Manner from Endogenous IFN Signaling

Respiratory syncytial virus (RSV) infection upregulates genes of the suppressor of cytokine signaling (SOCS) family, which utilize a feedback loop to inhibit type I interferon dependent antiviral signaling pathway. Here, we reconstituted RSV nonstructural (NS) protein expression plasmids (pNS1, pNS2...

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Detalles Bibliográficos
Autores principales: Zheng, Junwen, Yang, Pu, Tang, Yan, Pan, Zishu, Zhao, Dongchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628668/
https://www.ncbi.nlm.nih.gov/pubmed/26557722
http://dx.doi.org/10.1155/2015/738547