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Inhibition of PI3K Signalling Selectively Affects Medulloblastoma Cancer Stem Cells

Medulloblastoma is the most common malignant brain tumor of childhood. Although survival has slowly increased in the past years, the prognosis of these patients remains unfavourable. In this context, it has been recently shown that the intracellular signaling pathways activated during embryonic cere...

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Detalles Bibliográficos
Autores principales: Frasson, Chiara, Rampazzo, Elena, Accordi, Benedetta, Beggio, Giacomo, Pistollato, Francesca, Basso, Giuseppe, Persano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628705/
https://www.ncbi.nlm.nih.gov/pubmed/26557719
http://dx.doi.org/10.1155/2015/973912