PLK-1 Targeted Inhibitors and Their Potential against Tumorigenesis

Mitotic kinases are the key components of the cell cycle machinery and play vital roles in cell cycle progression. PLK-1 (Polo-like kinase-1) is a crucial mitotic protein kinase that plays an essential role in both the onset of G2/M transition and cytokinesis. The overexpression of PLK-1 is strongly...

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Detalles Bibliográficos
Autores principales: Kumar, Shiv, Kim, Jaebong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628734/
https://www.ncbi.nlm.nih.gov/pubmed/26557691
http://dx.doi.org/10.1155/2015/705745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628734/
https://www.ncbi.nlm.nih.gov/pubmed/26557691
http://dx.doi.org/10.1155/2015/705745

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