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PLK-1 Targeted Inhibitors and Their Potential against Tumorigenesis

Mitotic kinases are the key components of the cell cycle machinery and play vital roles in cell cycle progression. PLK-1 (Polo-like kinase-1) is a crucial mitotic protein kinase that plays an essential role in both the onset of G2/M transition and cytokinesis. The overexpression of PLK-1 is strongly...

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Detalles Bibliográficos
Autores principales:	Kumar, Shiv, Kim, Jaebong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628734/ https://www.ncbi.nlm.nih.gov/pubmed/26557691 http://dx.doi.org/10.1155/2015/705745

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