Helicobacter pylori CagA Suppresses Apoptosis through Activation of AKT in a Nontransformed Epithelial Cell Model of Glandular Acini Formation

H. pylori infection is the most important environmental risk to develop gastric cancer, mainly through its virulence factor CagA. In vitro models of CagA function have demonstrated a phosphoprotein activity targeting multiple cellular signaling pathways, while cagA transgenic mice develop carcinomas...

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Detalles Bibliográficos
Autores principales: Vallejo-Flores, Gabriela, Torres, Javier, Sandoval-Montes, Claudia, Arévalo-Romero, Haruki, Meza, Isaura, Camorlinga-Ponce, Margarita, Torres-Morales, Julián, Chávez-Rueda, Adriana Karina, Legorreta-Haquet, María Victoria, Fuentes-Pananá, Ezequiel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628739/
https://www.ncbi.nlm.nih.gov/pubmed/26557697
http://dx.doi.org/10.1155/2015/761501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628739/
https://www.ncbi.nlm.nih.gov/pubmed/26557697
http://dx.doi.org/10.1155/2015/761501

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