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All-Trans Retinoic Acid Induces Proliferation, Survival, and Migration in A549 Lung Cancer Cells by Activating the ERK Signaling Pathway through a Transcription-Independent Mechanism

All-trans retinoic acid (ATRA) has been used as an antineoplastic because of its ability to promote proliferation, inhibition, and differentiation, primarily in leukemia; however, in other types of cancer, such as lung cancer, treatment with ATRA is restricted because not all the patients experience...

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Detalles Bibliográficos
Autores principales: Quintero Barceinas, Reyna Sara, García-Regalado, Alejandro, Aréchaga-Ocampo, Elena, Villegas-Sepúlveda, Nicolás, González-De la Rosa, Claudia Haydée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628773/
https://www.ncbi.nlm.nih.gov/pubmed/26557664
http://dx.doi.org/10.1155/2015/404368