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All-Trans Retinoic Acid Induces Proliferation, Survival, and Migration in A549 Lung Cancer Cells by Activating the ERK Signaling Pathway through a Transcription-Independent Mechanism
All-trans retinoic acid (ATRA) has been used as an antineoplastic because of its ability to promote proliferation, inhibition, and differentiation, primarily in leukemia; however, in other types of cancer, such as lung cancer, treatment with ATRA is restricted because not all the patients experience...
Autores principales: | Quintero Barceinas, Reyna Sara, García-Regalado, Alejandro, Aréchaga-Ocampo, Elena, Villegas-Sepúlveda, Nicolás, González-De la Rosa, Claudia Haydée |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628773/ https://www.ncbi.nlm.nih.gov/pubmed/26557664 http://dx.doi.org/10.1155/2015/404368 |
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