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Heparan Sulfate Proteoglycans May Promote or Inhibit Cancer Progression by Interacting with Integrins and Affecting Cell Migration

The metastatic disease is one of the main consequences of tumor progression, being responsible for most cancer-related deaths worldwide. This review intends to present and discuss data on the relationship between integrins and heparan sulfate proteoglycans in health and cancer progression. Integrins...

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Detalles Bibliográficos
Autores principales: Soares, Mariana A., Teixeira, Felipe C. O. B., Fontes, Miguel, Arêas, Ana Lúcia, Leal, Marcelo G., Pavão, Mauro S. G., Stelling, Mariana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628971/
https://www.ncbi.nlm.nih.gov/pubmed/26558271
http://dx.doi.org/10.1155/2015/453801