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The Selectivity of CK2 Inhibitor Quinalizarin: A Reevaluation

Many polyphenolic compounds have been reported to inhibit protein kinases, with special reference to CK2, a pleiotropic serine/threonine kinase, implicated in neoplasia, neurodegenerative disease, and viral infections. In general however these compounds are not endowed with stringent selectivity. Am...

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Detalles Bibliográficos
Autores principales: Cozza, Giorgio, Venerando, Andrea, Sarno, Stefania, Pinna, Lorenzo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628998/
https://www.ncbi.nlm.nih.gov/pubmed/26558278
http://dx.doi.org/10.1155/2015/734127