CMP-Neu5Ac Hydroxylase Null Mice as a Model for Studying Metabolic Disorders Caused by the Evolutionary Loss of Neu5Gc in Humans

The purpose of this study was to identify the modification/turnover of gene products that are altered in humans due to evolutionary loss of Neu5Gc. CMP-Neu5Ac hydroxylase- (Cmah-) deficient mice show the infiltration of Kupffer cells within liver sinusoids, whereas body and liver weight develop norm...

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Detalles Bibliográficos
Autores principales: Kwon, Deug-Nam, Choi, Yun-Jung, Cho, Ssang-Goo, Park, Chankyu, Seo, Han Geuk, Song, Hyuk, Kim, Jin-Hoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629002/
https://www.ncbi.nlm.nih.gov/pubmed/26558285
http://dx.doi.org/10.1155/2015/830315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629002/
https://www.ncbi.nlm.nih.gov/pubmed/26558285
http://dx.doi.org/10.1155/2015/830315

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