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Combined use of phospholipid complexes and self-emulsifying microemulsions for improving the oral absorption of a BCS class IV compound, baicalin

The aim of this study was to develop a formulation to improve the oral absorption of baicalin (BA) by combining a phospholipid complex (PC) and self-emulsifying microemulsion drug delivery system (SMEDDS), termed BA–PC–SMEDDS. BA–PC was prepared by a solvent evaporation method and evaluated by compl...

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Detalles Bibliográficos
Autores principales: Wu, Huiyi, Long, Xiaoying, Yuan, Fei, Chen, Li, Pan, Sujing, Liu, Yunjun, Stowell, Yoshiko, Li, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629064/
https://www.ncbi.nlm.nih.gov/pubmed/26579386
http://dx.doi.org/10.1016/j.apsb.2014.03.002