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Combined use of phospholipid complexes and self-emulsifying microemulsions for improving the oral absorption of a BCS class IV compound, baicalin
The aim of this study was to develop a formulation to improve the oral absorption of baicalin (BA) by combining a phospholipid complex (PC) and self-emulsifying microemulsion drug delivery system (SMEDDS), termed BA–PC–SMEDDS. BA–PC was prepared by a solvent evaporation method and evaluated by compl...
Autores principales: | Wu, Huiyi, Long, Xiaoying, Yuan, Fei, Chen, Li, Pan, Sujing, Liu, Yunjun, Stowell, Yoshiko, Li, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629064/ https://www.ncbi.nlm.nih.gov/pubmed/26579386 http://dx.doi.org/10.1016/j.apsb.2014.03.002 |
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