Cargando…

Synthesis and biological evaluation of sophocarpinic acid derivatives as anti-HCV agents

Chronic hepatitis C virus (HCV) infection has become a major public health burden worldwide. Twenty-two sophocarpinic acid or matrine derivatives were synthesized and their anti-HCV activities were evaluated in vitro. The structure-activity analysis revealed that (i) sophocarpinic acids with a D-sec...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yinghong, Peng, Zonggen, Gao, Limei, Song, Danqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629077/
https://www.ncbi.nlm.nih.gov/pubmed/26579400
http://dx.doi.org/10.1016/j.apsb.2014.06.002