Establishment of drug-resistant HBV small-animal models by hydrodynamic injection

In antiviral therapy of hepatitis B virus (HBV) infection, drug resistance remains a huge obstacle to the long-term effectiveness of nucleoside/tide analogs (NAs). Primary resistance mutation (rtM204V) contributes to lamivudine (LAM)-resistance, and compensatory mutations (rtL180M and rtV173L) resto...

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Detalles Bibliográficos
Autores principales: Cheng, Junjun, Han, Yanxing, Jiang, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629082/
https://www.ncbi.nlm.nih.gov/pubmed/26579395
http://dx.doi.org/10.1016/j.apsb.2014.06.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629082/
https://www.ncbi.nlm.nih.gov/pubmed/26579395
http://dx.doi.org/10.1016/j.apsb.2014.06.009

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