Preclinical investigation of the pharmacokinetics, metabolism, and protein and red blood cell binding of DRDE-07: a prophylactic agent against sulphur mustard

DRDE-07, a newly synthesized amifostine analog currently under clinical investigation in a phase I trial, is a potent antidote against sulfur mustard toxicity. The purpose of this research was to evaluate the pharmacokinetic profile of DRDE-07 in female Swiss Albino mice after a single oral dose of...

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Detalles Bibliográficos
Autores principales: Verma, Pankaj, Vijayaraghavan, Rajagopalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629098/
https://www.ncbi.nlm.nih.gov/pubmed/26579409
http://dx.doi.org/10.1016/j.apsb.2014.08.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629098/
https://www.ncbi.nlm.nih.gov/pubmed/26579409
http://dx.doi.org/10.1016/j.apsb.2014.08.002

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