Assessment by HPLC of the degradation behavior of acitretin under hydrolytic, oxidative, photolytic and thermal stress conditions

Acitretin is a photosensitive oral retinoid with very limited data available on its degradation. The official HPLC method for acitretin determination was insufficient to resolve the degradation products generated during stability studies. Therefore, an isocratic RP-HPLC–UV method was developed for t...

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Detalles Bibliográficos
Autores principales: Porwal, Pawan K., Upmanyu, Neeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629101/
https://www.ncbi.nlm.nih.gov/pubmed/26579415
http://dx.doi.org/10.1016/j.apsb.2014.08.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629101/
https://www.ncbi.nlm.nih.gov/pubmed/26579415
http://dx.doi.org/10.1016/j.apsb.2014.08.004

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