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ETME, a novel β-elemene derivative, synergizes with arsenic trioxide in inducing apoptosis and cell cycle arrest in hepatocarcinoma cells via a p53-dependent pathway

Arsenic trioxide (ATO) has been identified as an effective treatment for acute promyelocytic leukemia (APL) but is much less effective against solid tumors such as hepatocellular carcinoma (HCC). In the search for ways to enhance its therapeutic efficacy against solid tumors, we have examined its us...

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Detalles Bibliográficos
Autores principales: Yu, Zhiying, Wu, Fangling, Chen, Liang, Li, Qian, Wang, Chaojie, Dong, Jinhua, Xie, Song-qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629106/
https://www.ncbi.nlm.nih.gov/pubmed/26579413
http://dx.doi.org/10.1016/j.apsb.2014.10.001