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Solid lipid nanoparticles for nose to brain delivery of haloperidol: in vitro drug release and pharmacokinetics evaluation

In the present study, haloperidol (HP)-loaded solid lipid nanoparticles (SLNs) were prepared to enhance the uptake of HP to brain via intranasal (i.n.) delivery. SLNs were prepared by a modified emulsification–diffusion technique and evaluated for particle size, zeta potential, drug entrapment effic...

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Detalles Bibliográficos
Autores principales: Yasir, Mohd, Sara, Udai Vir Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629108/
https://www.ncbi.nlm.nih.gov/pubmed/26579417
http://dx.doi.org/10.1016/j.apsb.2014.10.005