Synthesis of taurine–fluorescein conjugate and evaluation of its retina-targeted efficiency in vitro

In this work, retinal penetration of fluorescein was achieved in vitro by covalent attachment of taurine to fluorescein, yielding the F–Tau conjugate. Nuclear magnetic resonance (NMR) and high resolution mass spectrometry (HRMS) were used to confirm the successful synthesis of F–Tau. The cellular up...

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Detalles Bibliográficos
Autores principales: Huang, Meihong, Song, Jiaqi, Lu, Bingzheng, Huang, Huizhi, Chen, Yizhen, Yin, Wei, Zhu, Wenbo, Su, Xinwen, Wu, Chuanbin, Hu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629109/
https://www.ncbi.nlm.nih.gov/pubmed/26579416
http://dx.doi.org/10.1016/j.apsb.2014.10.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629109/
https://www.ncbi.nlm.nih.gov/pubmed/26579416
http://dx.doi.org/10.1016/j.apsb.2014.10.006

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